Impacto de la terapia inhalada con ˋ-2 agonistas de larga duraci車n sobre la calidad de vida en pacientes asm芍ticos

作者：Vegazo Garcia; O; Martin Fernandez; J; Barcina Sanchez; C; Jimenez Jimenez; F J; Estiarte Navarro; R

来源：Anales de Medicina Interna, 2004.

DOI：10.4321/S0212-71992004000600004

• asthma
• quality of life
• adrenergic beta-agonist
• therapies
• questionnaires.

objective: to assess the impact of the addition of inhaled therapy with long acting ˋ2 -agonists (formoterol) on the health related quality of life (hrql) in asthmatic patients treated with inhaled corticosteroids and poorly controlled. methods: observational prospective naturalistic study with a cohort of 343 ambulatory patients during 6 months. we collected socio-demographic, clinical and lung function variables. the hrql was assessed by means of a generic scale (sf-36) and a specific one (marks%26apos;s aqlq). results: they were evaluated 268 patients (78%). mean age 48.6 years (sd 16.28), 64.15% women. women and the subjects with worse socioeconomic situation had poor basal hrql scores. during the follow-up an average improvement in fev1 of 0.26 l (sd 0.44; p 0.5). conclusion: to add long acting ˋ2 -agonists to the asthmatic patients treated with inhaled corticosteroids and poorly controlled, under usual clinical practice conditions, is associated with an improvement of the hrql perception measured by means of generic and specific instruments.