Serum miR‐122 and miR‐192 as biomarkers of intrinsic and idiosyncratic acute hepatotoxicity: A quantitative real‐time polymerase chain reaction study in adult albino rats

作者：Abdelmonem G Madboly MD; Naglaa F Alhusseini MD; Shaymaa M Abd El Rahman MD; Walaa B El Gazzar MD; Ahmed M M Idris MD

来源：Journal of Biochemical and Molecular Toxicology, 2019, 33(7).

DOI：10.1002/jbt.22321

• Biomarkers
• Hepatotoxicity
• Idiosyncratic
• Intrinsic
• MiR‐122
• MiR‐192
• Real‐time polymerase chain reaction

Abstract(#br)miR‐122 and miR‐192 were investigated as indicators of toxic liver injury caused by acetaminophen, but their role in idiosyncratic toxic liver injury remains controversial. So, this work aimed to assess and compare the expressions of miR‐122 and miR‐192 in two different types of toxic l...