摘要

<正>The events occurring before and soon after birth appear to impact an individual’s health throughout adulthood significantly.The pioneering work of David J. P. Barker studied the nutritional status of 2414 pregnant women and their offspring during the Dutch famine between 1944 and 1945, and convincingly connected undernutrition during pregnancy to the predisposition of offspring to many adult-onset diseases, including cardiovascular disease,