Uveal schwannoma in a brown-eyed dog

作者：Marlo Todd L.; Giuliano Elizabeth A.^*; Moore Cecil P.; Shaw Gillian C.; Teixeira Leandro B. C.

来源：Veterinary Ophthalmology, 2018, 21(2): 205-209.

DOI：10.1111/vop.12458

• canine
• intraocular
• schwannoma
• spindle cell tumor of blue-eyed dogs
• tumor
• uveal

An eleven-year-old, female spayed Boxer dog was diagnosed with a uveal schwannoma (formerly known as the spindle cell tumor of the blue-eyed dog or SCTBED) despite having a uniformly brown iris. The patient presented to emergency for ocular discomfort, and the right globe was subsequently enucleated due to glaucoma and submitted for histopathology. Upon histopathologic evaluation, a uveal schwannoma was diagnosed and confirmed with immunohistochemical staining. Complete metastatic evaluation 1 and 6 months after initial presentation did not reveal evidence of metastasis, and the dog remains systemically healthy. This case represents a unique variant of uveal schwannoma and is relevant because although the vast majority of these tumors occur in blue-eyed dogs, clinicians should not completely rule out this tumor as a differential based on the iris color.