科研之友
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摘要
Hyperlipidaemia is one of the major risk factors of cardiovascular complication in diabetes. A studywas undertaken to evaluate the antihyperlipidaemic activity of pterostilbene. Oral administration ofpterostilbene (40mg/kg bodyweight) to streptozotocin-nicotinamide induced diabetic rats for 6 weekssignificantly reduced the elevated serum very low density lipoprotein (VLDL) and low densitylipoprotein (LDL)-cholesterol levels and significantly increased the serum high-density lipoprotein(HDL)-cholesterol level. In addition, pterostilbene also significantly lowered the levels of triglycerides,phospholipids, free fatty acids and total cholesterol in the serum, liver and kidney of diabetic rats.
