Red blood cell distribution width is associated with in-hospital mortality in sepsis with MRSA infection in MIMIC-Ⅳ

作者：Song Kun; Song Yaqin; Ding Ning^*; Li Changluo^*

来源：实用休克杂志(中英文), 2022, 6(06): 377-384.

Background This study aimed to explore the associations of factors with in-hospital mortality in sepsis with MRSA infection based on the MIMIC-Ⅳdatabase.Methods All sepsis patients with MRSA infection were included.Multivariate regression analysis was applied to identify predictive factors.Models were applied to explore the relationship between the factors and in-hospital mortality after adjusting potential cofounders.Results A total of 157 patients were included including a survivor group (n=111)and a non-survivor group (n=46)were included.RDW was identified as an independent factor with in-hospital mortality.A smooth fitting curve for a positive linear relationship between RDW and in-hospital mortality was constructed.The area under the ROC curve(AUC)was 0.652 with a sensitivity of 0.565 and a specificity of 0.676.The optimal cut-off value of RDW was 16.55.Compared with SOFA and APACHEⅡscores,RDW had a better predictive performance.Conclusion RDW was associated with clinical outcomes in sepsis with MRSA infection.