Surivin 启动子调控靶向IGF1R基因miR30-shRNA慢病毒的构建及抗肝癌细胞生长作用的研究(英文)

来源：The Chinese-German Journal of Clinical Oncology, 2011, (12): 705-710.

• RNA interference
• human insulin like growth factor receptor 1(human IGF1R)
• survivin promoter
• lentivirus RNA interference
• human insulin like growth factor receptor 1(human IGF1R)
• survivin promoter
• lentivirus

Objective:The aim of the study was to investigate the interference and anti-tumor effects of lentiviral vector of miRNA targeting IGF1R gene regulated by survivin promoter.Methods:The fragment of the survivin promoter was acquired by PCR amplification and inserted into pPRIME to recombinant plasmid ...