Stromal‐induced downregulation of miR‐1247 promotes prostate cancer malignancy

作者：Maria Letizia Taddei; Lorenzo Cavallini; Matteo Ramazzotti; Giuseppina Comito; Laura Pietrovito; Andrea Morandi; Elisa Giannoni; Giovanni Raugei; Paola Chiarugi

来源：Journal of Cellular Physiology, 2019, 234(6): 8274-8285.

DOI：10.1002/jcp.27679

• Anoikis resistance
• Cancer‐associated fibroblast
• MiR‐1247
• Neuropilin‐1
• Prostate cancer

Abstract(#br)Cancer progression is strictly dependent on the relationship between tumor cells and the surrounding stroma, which supports cancer malignancy promoting several crucial steps of tumor progression, including the execution of the epithelial to mesenchymal transition (EMT) associated with e...