Downregulation of miR‐1224 protects against oxidative stress‐induced acute liver injury by regulating hepatocyte growth factor

作者：Wenting Cheng; Guo‐pan Liu; Dehua Kong; Wei Huang; Ying Sun; Danmei Zhao

来源：Journal of Cellular Biochemistry, 2019, 120(8): 12369-12375.

DOI：10.1002/jcb.28502

• Acute liver injury
• Apoptosis
• Hepatocyte growth factor
• MicroRNA‐1224
• Oxidative stress

Abstract:(#br)Objective(#br)To study the effect of microRNA‐1224 (miR‐1224) on hydrogen peroxide (H2O2)‐induced oxidative stress injury in hepatocytes, and explore its underlying mechanism.(#br)Methods(#br)L02 cells were treated with H2O2 (100 mmol/L) to e...