Urtic芍ria

作者：Criado; Paulo Ricardo; Criado; Roberta Fachini Jardim; Maruta; Celina W; Martins; Jose Eduardo Costa; Rivitti; Evandro A

来源：Anais Brasileiros de Dermatologia, 2005.

DOI：10.1590/S0365-05962005000700008

• adrenal cortex hormones
• cyclosporine
• histamine
• histamine antagonists
• histamine h1 antagonists
• histamine h2 antagonists
• mast cells
• prostaglandins
• urticaria.

urticaria has diverse clinical presentations and causes. it is one of the most frequent dermatological conditions: 15% to 20% of population has at least one acute eruption during their lifetime, resulting in 1% to 2% of dermatological and allergological visits. urticaria is classified based on its temporal evolution as acute (less than 6 weeks) or chronic (more than 6 weeks). management strategies may involve non-pharmacological measures and drug interventions, which are grouped into first- (antihistamines), second- (corticosteroids and anti-leukotrienes) and third-line therapies (immunomodulators). stronger, but potentially riskier, second- and third-line management may be justified for patients who do not respond to first-line therapy, or whenever a specific etiology cannot be determined, such as in autoimmune urticaria.