ChemInform Abstract: An Efficient Organocatalytic Enantioselective Michael Addition of Aryl Methyl Ketones with 2‐Furanones: Highly Functionalized Chiral 3,4‐Substituted Lactones.

作者：Wei Wang; Junfeng Wang; Shuo Zhou; Qi Sun; Zemei Ge; Xin Wang; Runtao Li

来源：ChemInform, 2013, 44(22): no-no.

DOI：10.1002/chin.201322103

• furan derivatives
• diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism)
• C‐C bond formation
• addition reactions
• organocatalysis

The title reaction provides a convenient access to a wide variety of highly substituted chiral γ‐lactones with good yields and good to excellent enantioselectivities (22 examples).

• 单位
  北京大学