摘要

A maior suscetibilidade dos neonatos 角s infec es resulta em taxas de infec o hospitalar (IH) superiores 角s outras popula es de pacientes. O objetivo deste trabalho foi determinar a frequ那ncia e o perfil das IH para os neonatos associando os principais fatoresde risco e 車bito. Foi realizado estudo epidemiol車gico, retrospectivo, em registros de notifica o de infec es neonatais da Comiss o de Controle de Infec o Hospitalar do Hospital Universit芍rio de Londrina, no per赤odo entre 2001 e 2005. A taxa m谷dia anual deIH neonatal foi 18,3% ao longo dos cinco anos. As infec es mais frequentes foram pneumonia (46,0%) e sepse (49,1%), as quais estiveram relacionadas ao tempo de hospitaliza o superior a 60 dias e aos procedimentos invasivos como intuba o orotraqueale o cateterismo vascular, que aumentaram tr那s vezes o risco para sepse e respectivamente 3,26 e 2,50 vezes o risco para 車bito. A IH contribuiu com 85,7% dos 車bitos. O coeficiente de letalidade foi 15,8%. The greater susceptibility of neonates to infections results in higher rates of nosocomial infection (NIs) than in other patient populations. The objective of this work was to determine the frequency and profile of NIs in neonates associated to the main risk and death factors. A retrospective epidemiological study wasconducted on neonates with NIs admitted to the neonatal sector at the University Hospital of Londrina, between 2001 and 2005. The mean annual rate of neonatal NI was 18.3% over the course of five years. The most frequent infections were pneumonia (46.0%) and sepsis(49.1%), which were related to a hospitalization period of over 60 days. The use of tracheal tubes and vascular catheters increased threefold the risk of sepsis. The tracheal tubes and vascular catheters increased the risk of death by 3.26 and 2.50 times, respectively. NIs contributed to 85.7% of deaths. The mortality coefficient was 15.8%.

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