放射性药物治疗芯片:微流控驱动的数字孪生在个体化癌症治疗中的展望(英文)

作者:Hamid Abdollahi; Babak Saboury; Madjid Soltani; Kuangyu Shi; Carlos Uribe; Arman Rahmim*
来源:Science Bulletin, 2023, 68(18): 1983-1988.

摘要

<正>Radiopharmaceutical therapy(RPT) has shown great promise in the treatment of various cancers. However, the current approach is a ‘‘one size fits all” model, which results in varied patient responses, and there is a need for personalized RPT(Fig. S1 online).This personalized approach requires a better understanding of the physics, biology, radiobiology, pharmacology, immunology, chemistry, and imaging involved in RPT [1]. Multidisciplinary research using experimental, numerical, and simulation platforms would be key to accelerating progress in this area.