科研之友
微信
新浪微博
Facebook
分享链接
摘要
objective: to look for correlations between radiological patterns and cd4+ t cell counts in patients coinfected with tuberculosis and human immunodeficiency virus. methods: patients included were selected from among those presenting human immunodeficiency virus/tuberculosis coinfection and admitted to the nereu ramos hospital, located in florian車polis, brazil, between january of 2000 and december of 2003. results: a total of 87 patients were included. the mean age was 34 ㊣ 8 years, and 6.8% were non-caucasian. the mean cd4+ t cell count was 220.2 cells/mm3 (median, 144 cells/mm3), and 56.4% of the patients presented less than 200 cells/mm3. we identified the following radiographic patterns and related them to the cd4+ t cell counts: the alveolar pattern in 50.6% of the cases (56.8% cd4+ t cells %26lt; 200); the interstitial pattern in 32.2% (53.6% cd4+ t cells %26lt; 200); pleural effusion in 24.1% (47.6% cd4+ t cells %26lt; 200); cavitation in 24.1% (57.1% cd4+ t cells %26lt; 200); enlarged mediastinal or hilar lymph nodes in 11.5% (90% cd4+ t cells %26lt; 200); and a normal pattern in 11.5% (60% cd4+ t cells %26lt; 200). the mean cd4+ t cell counts for the radiologic patterns isolated were as follows: 235.2/mm3 (alveolar consolidation); 208.8/mm3 (interstitial); 243.3/mm3 (pleural effusion); 265/mm3 (cavitation); 115.1/mm3 (enlarged mediastinal or hilar lymph nodes) (p %26lt; 0.05); and 205.5/mm3 (presenting no radiological alterations). as noted, mediastinal/hilar lymph node enlargement was the only pattern that correlated with the degree of cell-mediated immunity in a statistically significant way. conclusion: with the exception of mediastinal/hilar lymph node enlargement, the radiographic patterns were randomly distributed in relation to the cd4+ t cell counts.
