科研之友
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摘要
Six geographic areas that deviated significantly from randomness were uncovered in the age-adjusted analyses of males: three with higher incidence rates than expected and eight lower than expected. In the age-adjusted analyses of females, one area with a higher incidence rate, and one area with a lower incidence rate than expected, were found. After adjustment for SES and percent urban, some of these areas were no longer significantly different.Public health practitioners can use the results of this study to focus their attention onto areas in Massachusetts that need to increase colorectal screening or have elevated risk of colorectal cancer incidence.This observational epidemiological study of Massachusetts colorectal cancer incidence and proportion of late-stage examines the geographic variations over a four-year period. The investigation looks to determine whether observed excesses of incidence rates or proportion of late-stage cases occur at random or represent statistically significant deviations from randomness using purely spatial and space-time models. By modeling space and time, it is possible to determine whether these excesses are stable over time, or only temporary. The models were also adjusted for SES and percent urban to see if these factors could account for the significantly high and low areas. The study is part of the surveillance process in which the data are analyzed to identify areas where closer attention is needed and to aid in determining the need for public health programs or evaluate ones that are in place.A spatial analysis of a portion of Cape Cod, Massachusetts studied 1983每1986 and found no statistically significant variation of colorectal cancer incidence [1]. There have not been any studies published and indexed in PubMed that include all of Massachusetts in a spatial scan analysis evaluating colorectal cancer incidence. However, studies have looked into how factors such as socioeconomic status (SES) and urban/rural classifications of
