LGR4调节肿瘤中骨转移(英文)

作者:罗剑
来源:中国生理学会基质生物学专业委员会第二次全国基质生物学学术会议, 中国湖南吉首, 2017-06-07.

摘要

<正>Tumor necrosis factor(TNF)superfamily member 11(TNFSF11,also known as RANKL)regulates multiple physiological or pathological functions,including osteoclast differentiation and osteoporosis.TNFRSF11A(also called RANK)is considered to be the sole receptor for RANKL.Herein we report that leucine-rich repeat-containing G-protein-coupled receptor 4(LGR4,also called GPR48)is another receptor