Aspectos patol車gicos, imunol車gicos e propriedades moleculares do TT v赤rus

作者:Watanabe; Maria Angelica Ehara; Miranda; Helen Cristina; Oliveira; Karen Brajo de; Oliveira; Carlos Eduardo Coral de; Tristo; Fabrine Sales Massafera; Duarte; Leila Maria; Silva; Ligiane de Lourdes; Corte; Andreia Correa; Guarnier; Flavia Alessandra; Kaminami; Mari Sumigawa
来源:Jornal Brasileiro de Patologia e Medicina Laboratorial, 2005.
DOI:10.1590/S1676-24442005000400002

摘要

tt virus (ttv) was first reported in japan in 1997 by t. nishizawa in sera from non-a to non-g post-transfusion hepatitis patients. it has been intensively investigated, ever since, as a possible addition to the list of hepatitis-inducing viruses. the ttv is an unenveloped, single-stranded dna virus. considerable genetic variability of ttv has been demonstrated and has led investigators to group its isolates into numerous genotypes and subtypes. however, the clinical significance of ttv infection remains unknown. it is frequently detected in the serum and in other body fluids of humans. the component of ttv currently best understood is its genome. knowledge related to ttv has increased rapidly, but many fundamental aspects remain unclear. this review shows some of the molecular properties of tt virus.

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