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摘要
O presente trabalho objetivou an芍lise macrosc車pica e histol車gica do f赤gado de Leporinus macrocephalus para avaliar a estrutura do tecido hep芍tico. Os peixes provenientes de um pesqueiro da regi o de Bauru, Estado de S o Paulo, foram anestesiados, mortos, e os f赤gados foram retirados e encaminhados 角 rotina histol車gica, com inclus o em paraplast. A macroscopia mostrou um figado de estrutura homog那nea, de colora o marron-avermelhada, localizado na regi o medial do corpo, caudalmente ao cora o e posterior 角s branquias, apresentando tr那s l車bos de forma piramidal, sendo um central e dois laterais direito eesquerdo. A an芍lise histol車gica revelou o tecido hep芍tico constitu赤do por cord es duplos de hepat車citos circundados por sinus車ides, denominado de ※muralha dupla§. Revelou, ainda, um sistema biliar disperso pelo par那nquima hep芍tico mostrando ductos com epit谷lio c迆bicosimples, circundado por fibras musculares e tecido conjuntivo. C谷lulas do tecido pancre芍tico ex車crino foram observadas, margeando vasos sang邦赤neos, organizando-se em 芍cinos apresentando granulos de zimog那nio. Al谷m disso, existem centros melanomacr車fagos distribu赤dos ao longo de todo par那nquima, preferencialmente pr車ximos aos vasos sangu赤neos, formados por c谷lulas que acumulam materiais como melanina e lipofucsina, podendo sua presen a estar relacionada com o estado nutricional do peixe. The objective of this work was to analyze the liver of Leporinus macrocephalus at the macroscopic and histologic level by evaluating the characteristics of the hepatic tissue. The fishes from a fishery in Bauru, S.P., were collected and sacrificed by destroying the spinalcord; afterwards the collected hepatic tissue was fixed and followed by histological routine. Macroscopic analysis of L. macrocephalus liver showed an organ of homogeneous structure, with red-brown color, located in the medial region of the body, caudal to heart and after the gills. It showed 3 pyramidal lobes, one central and two lateral right and left. The histological analysis showed the hepatic tissue constituted by hepatocytes cords surrounded by sinusoids, named ※muralium duplex§. It yet revealed the diffused, distribution bile system by hepatic parenchyma, showing ducts with simple cubic epithelium, surrounded by muscular fibres and connective tissue. Cells of the exocrine pancreatic tissue were observed surrounding blood vessels in acinar arrangement as zymogen granules. Furthermore, there are melanomacrophages centers distributed along the hepatic parenchyma, preferably next to the blood vessels, constituted by cells accumulating mater
