Efeitos da radiaˋˋo solar crˋnica prolongada sobre o sistema imunol車gico de pescadores profissionais em Recife (PE), Brasil

作者：Bezerra; Sarita Maria de Fatima Martins de Carvalho; Sotto; Mirian Nakagami; Orii; Noemia Mie; Alves; Cleiton; Duarte; Alberto Jose da Silva

来源：Anais Brasileiros de Dermatologia, 2011.

DOI：10.1590/S0365-05962011000200004

• allergy and immunology
• antigens
• dermatology
• skin
• ultraviolet rays.

background: among the various occupations which necessarily require long-term and chronic sun exposure is that of a fisherman. however, clinical experience in dermatology earned over several years of medical practice does not seem to confirm this hypothesis. objective: to evaluate clinical, histological and immunological effects of long-term and chronic exposure to ultraviolet radiation in fishermen. methods: a prospective, cross-sectional and observational study characterized skin lesions, immunological markers and histological alterations in fishermen, as well as lymphocyte subpopulations compared to a control group. mann-whitney, fisher%26apos;s and wilcoxon statistical tests were used at a significance level of 0.05. results: there were significant differences between the exposed group and the group protected due to elastosis (p = 0.03), ectasia of dermal vessels (p = 0.012) and number of cells in the epidermal layers between cones (p = 0.029). most common among fishermen were cd45ro, cd68 + and mastocytes in the skin (p = 0.040, p %26lt;0.001, p = 0.001) and cd3cd8cd45ro in the blood (p = 0.016). conclusion: the alterations suggest that long-term and chronic sun exposure promotes tolerance to ultraviolet radiation, which protects against immunosuppression.