TGF-β_1,ADAM12和HB-EGF在原发性肝癌组织中的表达(英文)

来源：The Chinese-German Journal of Clinical Oncology, 2008, (12): 686-689.

• transforming growth factor-beta1
• a disintegrin and metalloprotease-12
• heparin-binding EGF-like growth factor
• hepatic carcinoma
• metastasis transforming growth factor-beta1
• a disintegrin and metalloprotease-12
• heparin-binding EGF-like growth factor
• hepatic carcinoma
• metastasis

Objective: To detect the expression and location of TGF-β1, ADAM12 and HB-EGF in primary hepatic carcinoma and study their effect on the growth and metastasis of hepatoma carcinoma cell. Methods: TGF-β1, ADAM12 and HB-EGF were detected by RT-PCR and immunohistochemistry in 30 cases of hepatic carcin...