Live birth following the transfer of an embryo with partial dissolution of zona pellucida on day 2: a case report and literature review [移植 1 枚第 2 日透明带部分消失的胚胎后活产的病例报道与文献复习]

作者：Liu S.; Wang M.; Huang G.; Wang F.; Fu L.; Zhang J.; Chen S.^*

来源：Chinese Journal of Reproduction and Contraception, 2022, 42(9): 948-951.

DOI：10.3760/cma.j.cn101441-20210329-00152

• Dissolution of zona pellucida
• Embryonic development
• Live birth

Objective To investigate the treatment of an embryo with the partial dissolution of zona pellucida on day 2 and summarize the identification and treatment of embryos without zona pellucida during culture. Methods A case of one live baby from an embryo with the partial dissolution of zona pellucida transferred on day 2 was retrospectively analyzed. Results Through reducing the transplant cleaning process, the patient got pregnant and delivered a live girl baby at 39+3 weeks of gestation. Conclusion The early dissolution of zona pellucida may affect the compaction process of embryos, but a good outcome can still be obtained by carefully selecting embryos and reducing the washing process of embryo transfer.