Research progress on historical evolution and modern development of Yiguan Decoction and prediction analysis on its quality marker (Q-Marker) [经典名方一贯煎的历史沿革、现代研究进展和质量标志物（Q-Marker）预测分析]

作者：Hu Y.-Y.; Chen L.; Li S.-P.; Aisa H.A.^*; Wu T.

来源：Chinese Traditional and Herbal Drugs, 2022, 53(23): 7585-7595.

DOI：10.7501/j.issn.0253-2670.2022.23.030

• azadirachtin
• bergapten
• betaine
• calorioside
• catalpanol
• falcarindiol
• ferulic acid
• ligustilide
• methylophiopogonanone A
• methylophiopogonanone B
• methylophiopogonone A
• methylophiopogonone B
• psoralen
• rehmannioside D
• ruscogenin
• senkyunolide I
• xanthotoxin
• Yiguan Decoction

Yiguan Decoction (一贯煎), a classical prescription of nourishing yin and soothing liver and treating yin deficiency of liver and kidney, is contained in the Xumingyi Leian written by Wei Zhixiu in the Qing Dynasty. Research progress on historical evolution and chemical constituent and pharmacological effect of Yiguan Decoction were reviewed in this paper. According to “five principles”, the quality markers (Q-Markers) of Yiguan Decoction were predicted in this paper. The results suggested that xanthotoxin, bergapten, psoralen, falcarindiol, methylophiopogonone A, methylophiopogonone B, methylophiopogonanone A, methylophiopogonanone B, ruscogenin, senkyunolide I, ligustilide, ferulic acid, catalpanol, rehmannioside D, calorioside, betaine and azadirachtin could be used as Q-Markers for Yiguan Decoction, which could provide basis and reference for the subsequent preparation of reference samples and further study of preparations.

• 单位
  中国科学院大学