Antibacterial activity and chemical composition of essential oil of Lippia microphylla Cham =Atividade antibacteriana e composi o qu赤mica do 車leo essencial de Lippia microphylla Cham

作者：Fabiola Fernandes Galvo Rodrigues; Henrique Douglas Melo Coutinho; Adriana Rolim Campos; Sidney Gonalo de Lima

来源：Acta Scientiarum - Biological Sciences, 2011.

• antibacterial activity
• 1
• 8-cineole
• verbenaceae
• Staphylococcus aureus
• atividade antibacteriana
• 1
• 8-cineol
• verbenaceae

The essential oil from the fresh leaves of Lippia microphylla Cham. was obtained by hydrodistillation and characterized by gas chromatography-mass spectrometry (GC-MS). Major constituents of the oil were 1.8-cineole (18.12%), 辰-ocimene (15.20%), bicyclogermacrene (11.63%) and caryophyllene oxide (8.32%). Antimicrobial activity of the oil against Gram-positive and Gram-negative bacteria was determined by gel diffusion method. The oil showed good antibacterial activity against Shigella flexneri, Escherichia coli and Streptococcus pyogenes and very good antibacterial activity against Staphylococcus aureus. O oleo essencial das folhas frescas de Lippia microphylla Cham. foi obtido por hidrodestilacao e caracterizado por cromatografia gasosa acoplada a espectrometria de massas (CG-EM). O constituinte majoritario do oleo foi 1.8-cineol (18,12%), 辰-ocimeno (15,20%), bicyclogermacreno (11,63%) e oxido de caryophylleno (8,32%). A atividade antimicrobiana do oleo frente as bacterias Gram-positivas e Gramnegativas foi determinada pelo metodo de difusao em gel. O oleo apresentou uma boa atividade antibacteriana frente a Shigella flexneri, Escherichia coli e Streptococcus pyogenes sendo o melhor resultado frente a Staphylococcus aureus.