Effective BI‐DIME Ligand for Suzuki–Miyaura Cross‐Coupling Reactions in Water with 500 ppm Palladium Loading and Triton X

作者：Nitinchandra D Patel; Dr Daniel Rivalti; Dr Frederic G Buono; Dr Arindom Chatterjee; Dr Bo Qu; Stefan Braith; Dr Jean‐Nicolas Desrosiers; Dr Sonia Rodriguez; Dr Joshua D Sieber; Dr Nizar Haddad; Dr Keith R Fandrick; Dr Heewon Lee; Dr Nathan K Yee; Dr Carl A Busacca; Dr Chris H Se

来源：Asian Journal of Organic Chemistry, 2017, 6(9): 1285-1291.

DOI：10.1002/ajoc.201700137

• cross-coupling
• green chemistry
• ligand effects
• micelles
• Suzuki–Miyaura reaction

Abstract(#br)An efficient, sustainable, and broadly applicable procedure has been developed for Suzuki–Miyaura cross‐coupling reactions in environmentally benign solvent (water) by employing as little as 500 ppm Pd(OAc)2 with a monophosphorus BI‐DIME ligand in the presence of inexpensive ...