科研之友
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摘要
purpose: to evaluate the effects of hiperbaric oxygen on the radiation-induced actinic lesions in the rat distal colon. methods: thirty-two wistar female rats were divided into four groups: i - sham; ii - hiperbaric oxygen therapy (hot); iii - radiotherapy (rt), e iv - radiotherapy and hiperbaric oxygen (the same manner of ii and iii group). fragments of distal colon were fixed into 10% formadehyde and proceeded for the histological routine and morphology. results: the experimental results showed the intestinal gland lesions, vasodilation and infiltrated leucocytes in propria laminae and submucosae in rat colon of giii that accentuated colon after hiperbaric oxygen conclusion: hiperbaric oxygen attenuated the morphological changes in the mucosae and submucosae of the rat distal colon with radiation-induced inflammatory process.
