Reduˋˋo dos linf車citos T-CD8+ citot車xicos observada com a terapia Puva em paciente com vitiligo

作者:Antelo; Daniela Pereira; Filgueira; Absalom Lima; Cunha; Jose Marcos Telles da
来源:Anais Brasileiros de Dermatologia, 2008.
DOI:10.1590/S0365-05962008000600013

摘要

the role of cytotoxic t cells (cd8+) has been emphasized in the pathogenesis of vitiligo. this cell population, identified by a skin homing molecule (cutaneous lymphocyte associated antigen a- cla), has been described in patients with other dermatoses and can be reduced with phototherapy. the authors present the case of a patient with generalized vitiligo and clinical recovery after puva parallel to a 25% reduction in cd8+-cla+ t cells in the peripheral blood.

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