摘要
the role of cytotoxic t cells (cd8+) has been emphasized in the pathogenesis of vitiligo. this cell population, identified by a skin homing molecule (cutaneous lymphocyte associated antigen a- cla), has been described in patients with other dermatoses and can be reduced with phototherapy. the authors present the case of a patient with generalized vitiligo and clinical recovery after puva parallel to a 25% reduction in cd8+-cla+ t cells in the peripheral blood.