科研之友
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摘要
background: in brazil, colorectal carcinoma (crc) is the third cause of death by malignant tumors among women and the fifth among men. objectives: to analyze the pathologic characteristics of crc in brazilian patients. material and methods: 486 crc diagnosed consecutively were studied. pathologic characteristics were analyzed according to the patients%26apos; gender and age and tumor location. results: crc was more frequent in women (n = 271; 56.9%) than in men (n = 205; 43.1%). the median age was 62.5 ㊣ 16.04 years and 51 (10.7%) were younger than 41 years. ulcer-infiltrative tumors were more common (n = 186; 40.8%) followed by annular-constrictive ones (n = 164; 36.0%). tumors raised at the right colon were significantly larger than those arising in the left colon (p %26lt; 0,001). most cases were moderately differentiated adenocarcinomas (n = 331; 69.8%), lymphatic vessels were invaded in 232 (52.7%), veins in 105 (23.9%) and nerves in 82 (18.5%). pt3 (n = 308; 64.7%) and pn0 (n = 246; 51.7%) were predominant; 168 (35.3%) crc were dukes b stage and 179 (37.6%) were dukes c. no association was found between tumor location and patients%26apos; gender, tumor histological type or stage. conclusions: our data are similar to those on record. they show that among our patients crc occurs predominantly in women and most tumors are detected in an advanced stage.
