抗胸腺细胞球蛋白如何在21世纪的单倍型供者造血干细胞移植中发挥重要作用（英文）

作者：Norbert Claude Gorin

来源：Science Bulletin, 2021, 66(24): 2445-2447.

<正>Hematopoeitic stem cell transplantation (HSCT) using a haploidentical family donor (HAPLO) was long thought to be non-feasible, essentially because of HLA incompatibility leading to graft rejection, severe acute (aGVH) and chronic (cGVH) graft versus host disease (GVH), severe infections and unacceptable nonrelapse mortality (NRM).