ChemInform Abstract: Highly Enantioselective Michael Addition of Diethyl Malonate to Chalcones Catalyzed by Cinchona Alkaloids‐Derivatived Bifunctional Tertiary Amine‐Thioureas Bearing Multiple Hydrogen‐Bonding Donors.

作者：Yulong Liu; Xie Wang; Xiaoyun Wang; Wei He

来源：ChemInform, 2014, 45(42): no-no.

DOI：10.1002/chin.201442077

• oxocarboxylic acids and esters (benzene compounds)
• addition reactions
• diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism)
• organocatalysis

Both catalysts used show excellent catalytic activities and enantioselectivities, giving the (R)‐ and (S)‐enantiomers of the adducts.