摘要

<正>Objective To evaluate the prognostic significance of combining ISS-Ⅲ and high risk cytogenetic abnormalities[HRCAs,including 1 q gain/amplification and del(17p)] in patients with newly-diagnosed multiple myeloma (NDMM).Methods The clinical characteristics and relevant variables were retrospectively analyzed in a total of 270 NDMM patients diagnosed between November 2009 and May 2018.ISS-Ⅲ stage and HRCAs [detected