Urotensin Ⅱ and urantide exert opposite effects on the cellular components of atherosclerotic plaque in hypercholesterolemic rabbits

作者：Qing-qing Yu; Da-xin Cheng; Li-ran Xu; Yan-kui Li; Xiao-ya Zheng; Yi Liu; Ya-feng Li; Hao-le Liu; Liang Bai; Rong Wang; Jiang-lin Fan; En-qi Liu; Si-hai Zhao

来源：Acta Pharmacologica Sinica, 2020, 41(4): 546-553.

• urotensin Ⅱ
• urantide
• atherosclerosis
• plaque
• macrophage

Increasing levels of plasma urotensin Ⅱ (UⅡ) are positively associated with atherosclerosis.In this study we investigated the role of macrophage-secreted UⅡ in atherosclerosis progression,and