New NIR-Ⅱ dyes without a benzobisthiadiazole core

作者：Hui Zhou; Yuling Xiao; Xuechuan Hong^*

来源：Chinese Chemical Letters, 2018, 29(10): 1425-1428.

Fluorescent NIR-Ⅱ imaging has a wide range of benefits not offered by other imaging modalities for biomedical applications, derived from its combination of high spatial and temporal resolution due to reduced photon absorption, scattering and tissue auto-fluorescence. Compared to the well-studied NIR-Ⅰ small-molecule fluorophores, the structures of NIR-Ⅱ fluorophores are scarce. To date, the main fluorophore units are composed of conjugated π system with a benzobisthiadiazole(BBTD) core and donor-acceptor-donor(D-A-D) structure. Herein, researchers Yang et al. and Zhang et al. have reported new NIR-Ⅱ probes ECX and FD-1080 respectively without a BBTD core which are highlighted.

• 单位
  病毒学国家重点实验室; 西藏大学