A PCR-based Rapid Neutralization Assay for GⅡ.4 Norovirus Infection in HIEC6 Cell Culture

作者:FAN Yi Sun; LIU Cheng; ZHU Hui Juan; DING Yi; ZENG Wan Jie; YIN Xu Fang; DING Shuang Shuang; ZHANG Jun
来源:Biomedical and Environmental Sciences, 2015, 28(03): 219-221.

摘要

<正>Because of limited viral replication and lack of cytopathic effect in cell culture,a new PCR-based rapid seroneutralization assay for detection of GII.4norovirus neutralized antibodies was developed with serum samples from acute-phase patients,convalescent-phase patients and healthy controls.According to this study,neutralizing antibodies were detected in 100% of