Progress in Research on Correlation Between Toll-like Receptors and Barrett's Esophagus [Toll样受体与Barrett食管相关性的研究进展]

作者：Yang N.; Jin S.^*; Li N.

来源：Chinese Journal of Gastroenterology, 2020, 25(12): 764-766.

DOI：10.3969/j.issn.1008-7125.2020.12.012

• Barrett Esophagus
• Inflammation
• Pathogenesis
• Toll-Like Receptors

Barrett's esophagus (BE), the only recognizable precancerous lesion of esophageal adenocarcinoma (EAC), is a common disease characterized by abnormal transformation of squamous epithelium into intestinal columnar epithelium. Toll-like receptors (TLRs) are important pattern recognition receptors that play a central role in innate and adaptive immunity. TLRs are involved in the identification of almost all pathogens. In addition, TLRs signaling pathway is important for the occurrence and development of BE. This article reviewed the progress in research on the correlation between TLRs and BE.

• 单位
  哈尔滨医科大学附属第二医院