科研之友
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摘要
objective: to compare individuals with and without hyperhidrosis in terms of the intensity of palmar and plantar sweating. methods: we selected 50 patients clinically diagnosed with palmoplantar hyperhidrosis and 25 normal individuals as controls. we quantified sweating using a portable noninvasive electronic device that has relative humidity and temperature sensors to measure transepidermal water loss. all of the individuals had a body mass index of 20-25 kg/cm2. subjects remained at rest for 20-30 min before the measurements in order to reduce external interference. the measurements were carried out in a climate-controlled environment (21-24oc). measurements were carried out on the hypothenar region on both hands and on the medial plantar region on both feet. results: in the palmoplantar hyperhidrosis group, the mean transepidermal water loss on the hands and feet was 133.6 ㊣ 51.0 g/m2/h and 71.8 ㊣ 40.3 g/m2/h, respectively, compared with 37.9 ㊣ 18.4 g/m2/h and 27.6 ㊣ 14.3 g/m2/h, respectively, in the control group. the differences between the groups were statistically significant (p %26lt; 0.001 for hands and feet). conclusions: this method proved to be an accurate and reliable tool to quantify palmar and plantar sweating when performed by a trained and qualified professional.
