Genome‐wide mRNA–miRNA profiling uncovers a role of the microRNA miR‐29b‐1‐5p/PHLPP1 signalling pathway in Helicobacter pylori ‐ driven matrix metalloproteinase production in gastric epithelial cells

作者:Chandreyee Datta; Arijita Subuddhi; Manish Kumar; Thurbu Tshering Lepcha; Sohini Chakraborty; Kuladip Jana; Zhumur Ghosh; Asish Kumar Mukhopadhyay; Joyoti Basu; Manikuntala Kundu
来源:Cellular Microbiology, 2018, 20(9): e12859.
DOI:10.1111/cmi.12859

摘要

Abstract(#br)Aberrant expression of microRNAs (miRNAs) is associated with tumour progression, extracellular matrix remodelling, and cell proliferation. miRNAs modulate host gene expression during infection by pathogens such as Helicobacter pylori , which is associated with varying degrees of gastric...