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摘要
Patients with schizophrenia have severe cognitive impairments. The important neurobiological basis of cognitive impairments is the abnormal level of neurotransmitters in the brain, which will lead to abnormal electrical activity of neurons. Electroencephalograph can be used to reflect the abnormal electrical activities caused by neurotransmitters objectively and quantitatively. Herein the researches on the neurobiology and electrophysiology of cognitive impairments in patients with schizophrenia at home and abroad are reviewed; the biological mechanisms of neurotransmitters related to cognitive impairments are analyzed; and the related abnormal bioelectrical indicators are sorted out, thus providing relevant reference for the pathogenesis study and auxiliary diagnosis of schizophrenia. In the future, more attention should be paid to the pathogenic genes, neuroimaging and other biological markers of the disease, and the establishment of an indicator system for the auxiliary diagnosis of schizophrenia. ? 2020 Chinese Journal of Medical Physics.
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