姜黄中3个新的没药烷型倍半萜类化合物

作者：Zhang Ying-Ying; Zhang Xuan; Li Wen-Chun; Chen Shao-Tian; Chen Jia^*

来源：Chinese Traditional and Herbal Drugs, 2023, 54(14): 4420-4426.

DOI：10.7501/j.issn.0253-2670.2023.14.002

• (±)-pinoresinol
• 11-hydroxy-bisabola-1,3(15),9-triene
• Curcuma longa L.
• turmerones G
• turmerones H

Objective To study the chemical constituents of hot water extraction from the root of Curcuma longa. Methods The various chromatographic techniques, such as macro-porous resin, silica gel column chromatographic and semi-prep HPLC were used isolate and purify compounds from the hot water extraction of C. longa root. The structures of these compounds were identified by analysis of physicochemical property and spectroscopic data. Results Ten compounds were isolated and identified as turmerones G (1), turmerones H (2), 11-hydroxy-bisabola-1,3(15),9-triene (3), vanillyl alcohol (4), bisacurone (5), bisacurone B (6), intermedin B (7), longpene C (8), 3-(4-hydroxy-3-methoxyphenyl)propane-1,2-diol (9), (±)-pinoresinol (10). Conclusion Compounds 1-3 are new compounds, wherein compounds 1 and 2 are epimers; And compounds 9, 10 were isolated from C. longa root for the first time. ? 2023 Editorial Office of Chinese Traditional and Herbal Drugs.

• 单位
  云南中医药大学