Advances in indole alkaloids from traditional Chinese medicine of Uncariae Ramulus Cum Uncis documented in Chinese Pharmacopoeia [《中国药典》收载的钩藤基原植物吲哚生物碱研究进展]

作者：Zhang J.-G.; Chen J.-J.; Geng C.-A.^*

来源：China Journal of Chinese Materia Medica, 2019, 44(4): 685-695.

DOI：10.19540/j.cnki.cjcmm.20181121.006

• Chemical constituents
• Indole alkaloids
• Uncaria
• Uncariae Ramulus Cum Uncis

Uncaria genus (Rubiaceae) contains 34 species all over the world, of which 11 species and one variant are present in China. Five species, namely U. rhynchophylla, U. macrophylla, U. hirsuta, U. sinensis and U. sessilifructus, are documented in Chinese Pharmacopoeia as the raw materials of Uncariae Ramulus Cum Uncis. Indole alkaloids are the characteristic constituents of Uncaria plants, in addition to triterpenes, lignans and flavones. This paper reviews the progress of indole alkaloids and their distribution within the five Uncaria species documented in Chinese Pharmacopoeia for better understanding the active constituents of Uncariae Ramulus Cum Uncis.

• 单位
  中国科学院大学; 中国科学院昆明植物研究所; 植物化学与西部植物资源持续利用国家重点实验室