采用RNAi技术抑制PeroxiredoxinⅠ的表达

作者：章波; 艾国平; 王燕; 王峰超; 白云; 粟永萍

来源：中国生物化学与分子生物学报, 2005, (05): 708-711.

DOI：10.13865/j.cnki.cjbmb.2005.05.028

• peroxiredoxin I
• ionizing radiation
• antioxidant protein
• RNAi
• inhibited expression peroxiredoxin I
• inhibited expression

Peroxiredoxin Ⅰ(PrxⅠ) is involved in many important cellular progresses such as cell proliferation and differentiation. To further elucidate its roles in ionizing radiation, eukaryotic expression vector containing siRNA targeting mRNA of peroxiredoxin 1 gene was constructed and transected into NIH3T...

• 单位
  创伤、烧伤与复合伤研究国家重点实验室; 第三军医大学