摘要

<正>In 1947, an original report describing the use of stereotactic-driven lesioning of the human brain triggered the onset of the functional neurosurgery era; during the 1950s, this lesioning approach began to be applied to the treatment of patients suffering from refractory epilepsy and movement disorders (Text S1 online).Concurrently, therapeutic alterations in brain activity were mainly achieved through focal interventions in anatomical brain structures thought to cause pathological clinical states. However,