Risco de infecˋˋo pelo Mycobacterium tuberculosis entre alunos da Faculdade de Medicina da Universidade Federal do Rio de Janeiro

作者：Silva; Vania Maria Carneiro da; Cunha; Antnio Jose Ledo Alves da; Kritski; Afranio Lineu

来源：Jornal Brasileiro de Pneumologia, 2004.

DOI：10.1590/S1806-37132004000500010

• ppd
• tuberculosis-infection
• tuberculin conversion
• medical students.

introduction: there have been few latin american studies investigating the fact that the rate of tuberculosis (tb) infection among medical students is higher than the 1.3% rate seen in the population at large. objective: to describe the cumulative incidence and the relative risk for tb infection among medical students. method: in 1998, a prospective cohort study was conducted involving medical students at the universidade federal do rio de janeiro faculdade de medicina who tested negative (induration %26lt;10 mm) on the tuberculin skin test (tst). students were tested using the two-step tst method and were retested one year later. the students tested were at two different stages in their training: pre-clinical (no contact with patients) and final year (contact with patients). information about demographic characteristics, bcg vaccination history, and instances of potential exposure to mycobacterium tuberculosis were obtained using a standardized questionnaire. of the 575 students initially enrolled, 72% (414) completed the study. results: the tsts of 16 (3.9%) of the 414 students converted, representing a cumulative incidence of 3.9% (95% confidence interval = 1.06 to 12.1). senior medical students were at an almost fourfold higher risk for m. tuberculosis infection than were those in pre-clinical training. conclusion: the risk for tst conversion is very high in this population.