衰老和疾病相关的认知功能下降:表观遗传生物标志物及治疗靶点（英文）

作者：张娟; 刘强^*

来源：Science Bulletin, 2023, 68(16): 1719-1721.

• 治疗靶点
• 生物标志物

<正>Epigenetic mechanisms, including DNA methylation, histone modification, and non-coding RNAs(ncRNAs), have been widely implicated in synaptic plasticity, memory formation, and memory consolidation. Dysregulation in epigenetic mechanisms has been reported in aged brains as well as age-related diseases, such as Alzheimer’s disease(AD).

• 单位
  中国科学技术大学; 中国科学院