科研之友
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摘要
objectives: to determine the levels of high sensitivity c-reactive protein (hscrp) in children/adolescents with and without obesity and their correlation with body mass index (bmi) and clinical and laboratory variables. methods: a cross-sectional study comparing two parallel groups, one a group of overweight or obese children/adolescents (obesity group, n = 131) and the other a control group of children/adolescents without obesity (control group, n = 114). high sensitivity nephelometry was used to determine hscrp concentrations. results: the obesity group exhibited greater hscrp concentrations than the control group (p %26lt; 0.0005). there were relationships between hscrp and bmi (p %26lt; 0.0001) and hscrp and triglycerides (p = 0.05). the relationship between hscrp and triglycerides was attenuated by adjustment for bmi, losing its statistical significance (p = 0.10). conclusions: the hscrp concentrations increased as bmi increased. the majority of individuals who were not overweight exhibited hscrp concentrations of less than 2 mg/l.
