Gold-Nanoparticle-Mediated Jigsaw-Puzzle-like Assembly of Supersized Plasmonic DNA Origami

作者：Yao, Guangbao; Li, Jiang; Chao, Jie; Pei, Hao; Liu, Huajie; Zhao, Yun; Shi, Jiye; Huang, Qing; Wang, Lianhui; Huang, Wei; Fan, Chunhai^*

来源：Angewandte Chemie - International Edition, 2015, 54(10): 2966-2969.

DOI：10.1002/anie.201410895

• DNA origami
• gold
• nanoparticles
• nanostructures
• self-assembly

DNA origami has rapidly emerged as a powerful and programmable method to construct functional nanostructures. However, the size limitation of approximately 100nm in classic DNAorigami hampers its plasmonic applications. Herein, we report a jigsaw-puzzle-like assembly strategy mediated by gold nanoparticles (AuNPs) to break the size limitation of DNA origami. We demonstrated that oligonucleotide-functionalized AuNPs function as universal joint units for the one-pot assembly of parent DNA origami of triangular shape to form sub-microscale super-origami nanostructures. AuNPs anchored at predefined positions of the super-origami exhibited strong interparticle plasmonic coupling. This AuNP-mediated strategy offers new opportunities to drive macroscopic self-assembly and to fabricate well-defined nanophotonic materials and devices.

• 单位
  中国科学院上海应用物理研究所; 南京邮电大学; 四川大学