Utility of 3-dimensional image reconstruction in the diagnosis of small-bowel masses in capsule endoscopy (with video)

作者：Rondonotti Emanuele^*; Koulaouzidis Anastasios; Karargyris Alexandros; Giannakou Andry; Fini Lucia; Soncini Marco; Pennazio Marco; Douglas Sarah; Shams Aman; Lachlan Neil; Zahid Ali; Mandelli Giovanna; Girelli Carlo

来源：Gastrointestinal Endoscopy, 2014, 80(4): 642-651.

DOI：10.1016/j.gie.2014.04.057

Background: In small-bowel capsule endoscopy (SBCE), differentiating masses (ie, lesions of higher probability for neoplasia) requiring more aggressive intervention from bulges (essentially, false-positive findings) is a challenging task; recently, software that enables 3-dimensional (3D) reconstruction has become available. %26lt;br%26gt;Objective: To evaluate whether %26quot;coupling%26quot; 3D reconstructed video clips with the standard 2-dimensional (s2D) counterparts helps in distinguishing masses from bulges. %26lt;br%26gt;Design: Three expert and 3 novice SBCE readers, blind to others and in a random order, reviewed the s2D video clips and subsequently the s2D clips coupled with their 3D reconstruction (2D+3D). %26lt;br%26gt;Setting: Multicenter study in 3 community hospitals in Italy and a university hospital in Scotland. %26lt;br%26gt;Patients: Thirty-two deidentified 5-minute video clips, containing mucosal bulging (19) or masses (13). %26lt;br%26gt;Intervention: 3D reconstruction of s2D SBCE video clips. %26lt;br%26gt;Main Outcome Measure: Differentiation of masses from bulges with s2D and 2D+3D video clips, estimated by the area under the receiver operating characteristic curve (AUC); interobserver agreement. %26lt;br%26gt;Results: AUC for experts and novices for s2D video clips was .74 and .5, respectively (P = .0053). AUC for experts and novices with 2D+3D was .70 (compared with s2D: P = .245) and .57 (compared s2D: P = .049), respectively. AUC for experts and novices with 2D+3D was similar (P = .1846). The interobserver agreement was good for both experts and novices with the s2D (k = .71 and .54, respectively) and the 2D+3D video clips (k = .58 in both groups). %26lt;br%26gt;Limitations: Few, short video clips; fixed angle of 3D reconstruction. %26lt;br%26gt;Conclusions: The adjunction of a 3D reconstruction to the s2D video reading platform does not improve the performance of expert SBCE readers, although it significantly increases the performance of novices in distinguishing masses from bulging.

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