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<正>Dear editor,Anaphylaxis and acute coronary syndromes(ACS) are discrete clinical presentations that usually present independently and are commonly treated in the emergency departments(EDs).[1] Kounis syndrome(KS) is a rare condition characterized by the coexistence of allergic reactions and ACS. KS was firstly described in detail by Kounis and Zavras in 1991 as an allergic angina syndrome.[2] The primary pathophysiological mechanism of KS is believed to be coronary artery vasospasm secondary to increased levels of infl ammatory mediators such as histamine, tryptase,
