Estudo da soropreval那ncia do AgHBs em gestantes da 15a Regional de Sa迆de e da imunoprofilaxia para os rec谷m-nascidos das gestantes AgHBs positivo = Study into the HBsAg seroprevalence in pregnant women from the 15th Health Regional and the immunoprophylaxia on the newborns of these HBsAg-positive women

作者：Sonia Kaori Miyamoto; Dennis Armando Bertolini

来源：Acta Scientiarum - Health Sciences, 2008.

• hepatite B
• AgHBs
• imunoprofilaxia
• CRIE
• gestantes
• soroprevalencia
• hepatitis B
• HBsAg
• immunoprophylaxis
• CRIE
• pregnant women
• seroprevalence

Determinar a preval那ncia do AgHBs nas gestantes da 15a Regional de Sa迆de (15a R.S.) atendidas no Laborat車rio de Ensino e Pesquisa em An芍lises Cl赤nicas (Lepac), Universidade Estadual de Maring芍, e verificar se foi solicitada a imunoprofilaxia para hepatite B aos rec谷m-natos das gestantes AgHBs positivo, no per赤odo de janeiro de 1998 a dezembro de 2002. A pesquisa do AgHBs foi realizada pela t谷cnica imunoenzim芍tica IMxHBsAg e Axsym HBsAg (Laborat車rio Abbott). As solicita es de imunobiol車gicos especiais para a imunoprofilaxia da hepatite B ao CRIE foram obtidas na Se o de Epidemiologia da 15a R.S. Foram analisadas 12.274 gestantes e a preval那ncia do AgHBs foide 1,0%. Dentre as 125 gestantes AgHBs positivo, foram solicitadas imunoprofilaxia para 32 (25,6%) rec谷m-nascidos. Ainda que a preval那ncia encontrada indique ser esta uma 芍rea de baixa endemicidade, os resultados reafirmam a importancia da realiza o do diagn車stico da hepatite B no atendimento pr谷-natal, para ado o da imunoprofilaxia no rec谷m-nascido. To determine HBsAg prevalence among pregnant women from the 15th Health Regional assisted in the Laborat車rio de Ensino e Pesquisa em An芍lises Cl赤nicas (Lepac), Universidade Estadual de Maring芍, and verify whether immunoprophylaxis with vaccine and immunoglobulin was requested for the newborns of HBsAg-positive women during the period from January 1998 to December 2002. The research about HBsAg was conducted using the immunoenzymatic IMxHBsAg (Abbot Lab) and Axsym HBsAg (Abbot Lab) techniques. The requests to the CRIE for specialimmunobiologic agents for Hepatitis B immunoprophylaxis were obtained in the Department of Epidemiology from the 15th Health Regional. The analysis includes 12,274 pregnant women, and the HBsAg prevalence was 1.0%. Among 125 HBsAg positive pregnant women, immunoprophylaxis was requested for 32 (25.6%) newborns. Although the prevalence detected demonstrates this to be a low endemic area, the results evidence theimportance of conducting the hepatitis B diagnostic during prenatal assistance, in order to perform immunoprophylaxis on the newborns.