EXTENDED SPECTRUM 汕-LACTAMASES (ESBL) IN UROPATHOGENIC ESCHERICHIA COLI, PREVALENCE AND SUSCEPTIBILITY PATTERN IN A SOUTH INDIAN CITY

作者：Nair T Bhaskaran; Bhat G Kishore; Pai Vidya; Shantharam Manjula

来源：International Journal of Research in Ayurveda and Pharmacy, 2011.

• Uropathogenic E.coli
• Extended spectrum &beta
• -lactamase
• Multiple Drug Resistance.

The treatment of Escherichia coli (E.coli) infections is becoming difficult because of multidrug resistance. Extended spectrum 汕-lactamase (ESBL) production among E.coli resulted in limitations of therapeutic option. In this study, 300 strains of uropathogenic E.coli strains were studied for ESBL production by disc approximation test and double disc synergy test. Antibiotic sensitivity pattern of ESBL producers and Non ESBL producers are performed by Kirby-Bauer＊s disc diffusion technique. 56% of uropathogenic E.coli strains were ESBL producers. High degree of antibiotic resistance to gentamycin, norfloxacin, cotrimoxazole was seen among ESBL producers. Both ESBL producers and non-ESBL producers were sensitive to imipenum (100%). ESBL producers were susceptible to amikacin (84%), nitrofurntoin (91%) respectively.