Synthesis and Bioactivities of Andrographolide Derivatives： New （-）-Limonidilactone AnaloguesSynthesis and Bioactivities of Andrographolide Derivatives： New （-）-Limonidilactone Analogues

作者：徐海伟; 姜平娟; 李伟义; 王俊峰; 刘宏民

来源：Chinese Journal of Chemistry, 2011, (10): 2114-2118.

• 穿心莲内酯
• 人工合成
• 类似物
• 生物活性
• 衍生物
• 立体选择性反应
• 抗肿瘤
• 化合物

In this study, a novel route to （-）-limonidilactone analogues 10, 11 by way of stereoselective reaction of andrographolide （5） from 8, 9 was reported. The anti-tumor and a-glucosidsae inhibition